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Scott speaks with Wired magazine's John Heilemann about his article in the November issue about Microsoft and the government anti-trust case against the software giant.

NPR's Richard Knox looks at how doctors in Maine have turned against their long-time allies, the pharmaceutical companies. At issue are high drug prices that the companies now charge. Doctors say prices have reached a level where many patients can't afford to take the drugs they need, severely affecting not only the patients, but also their ability to practice good medicine. Three major pharmaceutical companies stopped shipping their drugs to Maine in reaction to the state's drug price-control law, which most doctors support. The pullout has only escalated tensions between the once-friendly groups.

Andrea Bernstein, of member station WNYC, reports on the New York Republicans' efforts to find a candidate to fill Rick Lazio's congressional seat.

NPR's Adam Hochberg reports on a coal mine pond that gave way in eastern Kentucky, releasing 250-million gallons of thick black sludge that polluted streams, killed fish and cut off drinking water supplies. Cleanup is under way.

A federal court judge in Portland, Maine has issued a temporary injunction, preventing the state of Maine from carrying a new law intended to lower prescription drug prices. The drug industry sought the injunction, claiming that the law was unconstitutional because it attempts to force companies to negotiate discounts on drugs. The state has not yet decided whether to appeal the ruling. Charlotte Renner of Maine Public Radio reports.

Scott speaks with NPR's Brian Naylor about how Republican leaders and the President are odds over a tax and spending bill right before the election.

Linda talks to Dennis Boroczk, who is overseeing a project to retrofit a Boeing 747 airplane with an infrared telescope and doors that can open to allow the telescope to be used during flight at an altitude of 41-thousand feet. Boroczk is Program Manager at the Stratospheric Observatory for Infrared Astronomy at Raytheon Labs. The high-flying telescope will allow scientists to make infrared measurements of a variety of heavenly objects, such as stars, galaxies, and quasars. The effort is a joint project of between NASA and the German Aerospace Center, with Raytheon making the modifications.

With a little more than a week before Election day, things are heating up between the presidential campaigns. An ad supporting Governor Bush is causing some controversy. We have two reports, first from NPR's Anthony Brooks with the the Gore campaign, then NPR's Peter Kenyon with Governor Bush.

Noah talks to sportswriter Stefan Fatsis about the latest pro-basketball news, in advance of the National Basketball Association's new season, which starts next week. The Minnesota Timberwolves have been fined three-point-five million dollars and stripped of their next five first-round draft picks. The league says the Timberwolves violated the salary cap by making an under-the-table deal with player Joe Smith.

NPR's Larry Abramson reports on a cyber-break-in at Microsoft's headquarters this week. Microsoft says hackers accessed blueprints for software -- but didn't see codes for the most popular products such as Windows ME, Windows 2000 or Microsoft Office. The company said the programs that were involved were still under development and had not been corrupted or tampered with.